Search on: CYCLIN-DEPENDENT KINASE INHIBITOR P16 
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Descriptor English:   Cyclin-Dependent Kinase Inhibitor p16 
Descriptor Spanish:   Inhibidor p16 de la Quinasa Dependiente de Ciclina 
Descriptor Portuguese:   Inibidor p16 de Quinase Ciclina-Dependente 
Tree Number:   D12.644.360.225.200
D12.776.167.187.200
D12.776.476.225.200
D12.776.624.776.355.200
Definition English:   A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions. 
See Related English:   Genes, p16
Tumor Suppressor Protein p14ARF
 
History Note English:   2006(1994) 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   33490 
Unique Identifier:   D019941 

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